Crystal Structures

AvrM14 Interactive Model

AvrM14 is an mRNA decapping effector. It can also homodimerise and this alters the pyrophosphate bond hydrolysed when decapping mRNA. I determined the crystal structure of both monomeric (PDB ID 8DP9) and homodimeric (PDB ID 8DPA) AvrM14 protein.

MoNudix Interactive Model

MoNudix is an inositol pryophosphate hydrolase. I determined MoNudix's crystal structure (PDB ID 8SXS) and used this to direct functional characterisation.

AvrM14 Electron density map

Crystal structures are models built to explain experimental data. With the electron density maps, you can see how well a PDB file fits to the experimental data. Here is the electron density map of 8DP9.

MoNudix Electorn density map

And of 8SXS.